Scientists have found that Mallotus furetianus, a tropical plant native to China, has antiobesity potential. In a recent study, mice treated with the plant’s extract suppressed the increase in body and adipose tissue (body fat) weight.
The researchers also found changes in the liver and adipose tissue structure of obesity model mice. An in vitro investigation revealed that fat synthesis was inhibited by suppressing the expression of several transcription factors.
“Utilizing Mallotus furetianus as one of the tools for obesity prevention through consumption can contribute to reducing the obese population,” co-author Akiko Kojima, professor of the Graduate School of Human Life and Ecology at Osaka Metropolitan University, Japan, tells Nutrition Insight.
She notes that the study’s results suggest a link between Mallotus furetianus extract (MFE) and anti-obesity effects and indicate its potential as a new food ingredient with anti-obesity properties.
Body weight changes The researchers divided 36 mice into four groups, feeding them either a low-fat control diet, a high-fat diet, a control + MFE diet or a high-fat + MFE diet. After 32 days, the body weight of mice eating a high-fat diet was higher than mice eating a regular diet.
However, the body weight of mice consuming the extract with their high-fat diet was significantly lower than the group only eating the high-fat diet. Moreover, the researchers found that the body fat weight decreased when mice consumed the plant extract with their high-fat diet. In addition, adding MFE to a high-fat diet significantly suppressed the occurrence of fatty liver. Mice on the cont.
Nutrition Insights/August 8, 2023